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KMID : 0378019700130030048
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New Medical Journal
1970 Volume.13 No. 3 p.48 ~ p.54
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Experimental Studies on Renal allotransplantation in dogs Histological findings and preservation with continuous perfusion and hypothermia
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ÑÑâª÷Á/Kim, Soo Tae
ÑÑòÌüº/ÑÑéÔÐñ/ÚÓôÉФ/ûóñÕûÇ/çïáøÙ¥/êäÙ¥ñ£/Kim, Jin Whan/Kim, Woo Ki/Park, Hul Kyu/Hong, Jun Ho/Oh, Myung Soo/Yoo, Myung Jong
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Abstract
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Canine renal transplantation was done in this laboratory in 1969.
1. The six dogs of fourteen autografts were observed for six months. All of them showed weight gain from the postoperative immediate debilitated states at the end of postoperative one month.
2. The five dogs of renal homografts into an untreated recipients with immunosupnressive drug survived for seven days on the average.
3. In the eight cases of inguinal homografts treated with azathioprine or azathioprine and prednirsolone, the transplanted kidneys could discharge clear urine for 15 days on the average from -the ureterostomy on the abdominal wall. One of them continued urination until the postoperative 24th day at the time. of removing the graft.
4. The kidneys perfused using continuous flow rate of 320 m1/hr for three or four hours with 4¡ÆC 1,000 ml of Ringer¢¥s lactate solution containing heparin 50mg and procaine t gm revealed almost normal histological architectures.
5. The six homografts perfused for three hours using the above stated method could discharge clear urine for 4. 5 days on the average. One of them continued clear urination until the postoperative 7th day at the time of removing the graft.
6. The six homografts perfused for four hours using the same method continued urination for 3.8 days except one kidney which was missed due to death of the recipient from severe bleeding from the surface of the kidney within 24 hours after transplantation.
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